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Study of tocopherol content and its potential antioxidant activity in commercial lipid emulsions for parenteral nutrition

Journal Contribution - Journal Article

The objective of this study was to determine the content and evaluate the potential antioxidant effect of tocopherols in commercially available lipid emulsions, using a simple validated method adequate for further routine use. During the study, variability between manufacturers as well as between three non-consecutive batches of the same emulsion was observed. Furthermore, addition of α-tocopherol to lipid emulsions as excipient yields more stable emulsions and potentially a beneficial clinical effect. It was concluded that the variation of the tocopherol content between batches implies the importance of control and specification of tocopherol content by the manufacturers.
Journal: Die Pharmazie
ISSN: 0031-7144
Issue: 6
Volume: 75
Pages: 240 - 241
Publication year:2020
BOF-keylabel:yes
IOF-keylabel:yes
BOF-publication weight:0.5
CSS-citation score:1
Authors:International
Authors from:Higher Education
Accessibility:Open