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Publication
The peripheral olfactory code in Drosophila larvae contains temporal information and is robust over multiple timescales
Journal Contribution - Journal Article
We studied the electrophysiological activity of two classes of Drosophila melanogaster larval olfactory sensory neurons (OSNs), Or24a and Or74a, in response to 1 s stimulation with butanol, octanol, 2-heptanone, and propyl acetate. Each odour/OSN combination produced unique responses in terms of spike count and temporal profile. We used a classifier algorithm to explore the information content of OSN activity, and showed that as well as spike count, the activity of these OSNs included temporal information that enabled the classifier to accurately identify odours. The responses of OSNs during continuous odour exposure (5 and 20 min) showed that both types of neuron continued to respond, with no complete adaptation, and with no change to their ability to encode temporal information. Finally, we exposed larvae to octanol for 3 days and found only minor quantitative changes in OSN response to odours, indicating that the larval peripheral code is robust when faced with long-term exposure to odours, such as would be found in a natural context.
Journal: Proceedings of the Royal Society B, Biological Sciences
ISSN: 0962-8452
Issue: 1831
Volume: 283
Publication year:2016
BOF-keylabel:yes
IOF-keylabel:yes
BOF-publication weight:3
CSS-citation score:1
Authors:International
Authors from:Higher Education