Imaging techniques in the optimization of mechanical support for the failing heart-lung unit

The overall aim of this project is to investigate novel techniques that enable us to monitor hemodynamic effects of mechanical interventions better in an ICU population. The project consists of two main studies encompassing multiple research questions. In each study echocardiography is evaluated as a tool to monitor the effect of changes in cardiac loading conditions induced by mechanical interventions to the heart and/or the lungs. Since the importance of heart-lung interactions in patients with acute cardiac and/or respiratory disease, we require a comprehensive approach integration hemodynamic, imaging and biological parameters. We therefore study heart and lung as part of one unit that is supported or loaded by the same intervention. The types of mechanical support included are: mechanical ventilation, mechanical circulatory support (mostly the Impella pump) and in most patients a combination of both. The titles of the respective projects are:

1.       Strain analysis to evaluate (and optimize) right ventricular function in ARDS

2.       Echocardiography in the optimization of Impella support and mechanical ventilation for cardiogenic shock patients