Development and evaluation of particulate formulations for the selective delivery of antigens and immunpotentiators towards dendritic cells.

Developing effective vaccins against insidous pathogens such as HIV, Mycobacterium tuberculosis and HCV represents a major challenge and is likely to require the induction of potent T cell mediated immune responses. In this project we aim to develop a particulate carrier allowing the selective delivery of both antigens and immunpotentiators to dendritic cells in order to promote the induction of potent T cell mediated immune responses.