Bronsted Acid Catalyzed Tandem Defunctionalization of Biorenewable Ferulic acid and Derivates into Bio-Catechol

An efficientconversionof biorenewableferulicacidintobio-catechol hasbeendeveloped.Thetransformationcomprisestwoconsecutivedefunctionalizationsof the sub-strate,that is,C@O(demethylation)andC@C(de-2-carbox-yvinylation)bondcleavage,occurringin one step.The processonlyrequiresheatingof ferulicacidwithHCl(or H2SO4)ascatalystin pressurized hot water(25088C, 50 bar N2). Theversatilityis shownon avarietyof other(biorenewable)substratesyieldingup to 84%di- (catechol, resorcinol,hydro-quinone)andtrihydroxybenzenes(pyrogallol,hydroxyqui-nol),in mostcasesjust requiringsimpleextractionas work-up.

Publication year:2020

BOF-keylabel:yes

IOF-keylabel:yes

BOF-publication weight:6

CSS-citation score:2

Authors from:Higher Education

Accessibility:Open