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Biocompatibility of cyclopropylamine-based plasma polymers deposited at sub-atmospheric pressure on poly (ε-caprolactone) nanofiber meshes

Journal Contribution - Journal Article

Subtitle:Biocompatibility of cyclopropylamine-based plasma polymers deposited at sub-atmospheric pressure on poly (epsilon-caprolactone) nanofiber meshes
In this work, cyclopropylamine (CPA) monomer was plasma-polymerized on poly (epsilon-caprolactone) nanofiber meshes using various deposition durations to obtain amine-rich surfaces in an effort to improve the cellular response of the meshes. Scanning electron microscopy and X-ray photoelectron spectroscopy (XPS) were used to investigate the surface morphology and surface chemical composition of the PCL samples, respectively. The measured coating thickness was found to linearly increase with deposition duration at a deposition rate of 0.465 nm/s. XPS analysis revealed that plasma exposure time had a considerable effect on the surface N/C and O/C ratio as well as on amino grafting efficiency and amino selectivity. In addition, cell studies showed that cell adhesion and proliferation significantly improved for all coated samples.
Journal: NANOMATERIALS
ISSN: 2079-4991
Issue: 9
Volume: 9
Publication year:2019
BOF-keylabel:yes
IOF-keylabel:yes
BOF-publication weight:2
Authors:National
Authors from:Higher Education
Accessibility:Open