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Project

PET imaging of free running rats with a high resolution human scanner for simultaneous behavioral neuroscience and imaging

The feasibility to perform brain PET imaging in free running rats on the high resolution research tomograph (HRRT) is investigated. With its high resolution (2.5 mm) and large field-of-view (FOV) (31x25 cm transaxial x axial) this dedicated human brain scanner would be particularly suited to image free running rats in a large FOV. This study will open the way, for the first time, to simultaneous behavioral and PET imaging experiments in rat. We will make use of our rat brain tracking and motion correction technology that was developed to scan awake rats on small animal PET scanners with much smaller FOV. We will adapt this technology to enable the methodology to work with scanners with a larger FOV where the animals have much more movement freedom.
Date:1 Apr 2016 →  31 Mar 2017
Keywords:SMALL ANIMAL IMAGING, NEURO-IMAGING, BEHAVIOURAL NEUROSCIENCE, ANIMAL BRAIN RESEARCH
Disciplines:Medical imaging and therapy, Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing