Predicting outcome after total knee replacement surgery in patients with knee osteoatthritis

Factors predicting poor outcome in knee osteoarthritis patients following total knee jointreplacement (TKR) surgery will be investigated, with focus on the role of pain due toneuroplasticity (i.e. hyperexcitability of the central nervous system).This will increase insight in the success rate and reasons behind the highly varying satisfactionafter TKR and may help in future decision making regarding need for and timing of TKR, aswell as the needs for pre- and postsurgical rehabilitation.

Keywords:REHABILITATION, NEURONAL PLASTICITY, OSTEOARTHRITIS, NEUROSCIENCE

Disciplines:Orthopaedics, Surgery, Human movement and sports sciences, Nursing, Rehabilitation sciences