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Project

A platform to functionally assess clinically relevant respiratory parameters in small animal models for infectious and non-infectious pulmonary research.

This application relates to the purchase of new basic infrastructure, more specific a FlexiVent system from Emka Technologies. FlexiVent is a platform for standard respiratory research that can be used across many pulmonary applications and which has major advantages compared to the classical, non-invasive, unrestrained plethysmography because it is accurate, reproducible and proven. FlexiVent is much more capable of detecting pulmonary abnormalities via changes in functional residual capacity, total lung capacity, vital capacity, and compliance of the respiratory system. Furthermore, analysis of pulmonary functions via FlexiVent allows distinction between respiratory diseases in mice by clinically relevant variables and is therefore generally accepted as the standard in the functional evaluation of infectious and non-infectious pathological, respiratory disease models.
Date:1 Jan 2020 →  31 Dec 2021
Keywords:RESPIRATORY DISEASES, FUNCTIONAL RESPIRATORY ASSESSMENT, LOWER RESPIRATORY TRACT INFECTIONS, RESPIRATORY TRACT INFECTIONS
Disciplines:Inflammation, Bacteriology, Infectious diseases, Virology, Respiratory medicine