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Publication
Ru(TAP)32+ uses multivalent binding to accelerate and constrain photo-adduct formation on DNA
Journal Contribution - Journal Article
Ru(ii)-complexes with polyazaaromatic ligands can undergo direct electron transfer with guanine nucleobases on blue light excitation that results in DNA lesions with phototherapeutic potential. Here we use single molecule approaches to demonstrate DNA binding mode heterogeneity and evaluate how multivalent binding governs the photochemistry of [Ru(TAP)3]2+ (TAP = 1,4,5,8-tetraazaphenanthrene).
Journal: Chemical Communications
ISSN: 1359-7345
Issue: 60
Volume: 55
Pages: 8764 - 8767
Publication year:2019
BOF-keylabel:yes
IOF-keylabel:yes
BOF-publication weight:2
CSS-citation score:1
Authors:International
Authors from:Higher Education