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Project

Statistical methodology for epidemiological and clinical research in childhood and maternal health in the context of mother to child transmission of HIV and other infectious diseases (R-5044)

The objectives of this project are as follows. The efficacy and effectiveness of the strategy termed Option B+ will be evaluated, in an effort to reduce mother-to-child transmission of HIV infection. Epidemiological and clinical trial methodology will be combined to this effect. Also, the practical feasibility of the strategy towards health care facilities, communities, but also patients, will be studied. For the latter, particular attention will be paid to patient compliance and measures to increase it. A model will be built to describe and explain waiting times for patients with appointments in health centers. Further, a prediction model will be built for the next appointment, so that a descriptive model can be turned into a pro-active one. Methodology from clinical trials, epidemiological studies, survey sampling techniques, longitudinal data analysis, joint modeling of survival and longitudinal outcomes, and overdispersion modeling will be combined in view of the said goals.
Date:1 Jan 2014 →  31 Dec 2015
Keywords:EPIDEMIOLOGY AND PUBLIC HEALTH, MODELS INFECTIOUS DISEASES
Disciplines:Health sciences