Molecular characterization of the neuroprotective role of signalling molecules enriched extracellular vesicles (R-9497)

One of the most common brain disorders and cause of disability in young adults is the chronic auto-immune disease multiple sclerosis (MS) with worldwide, an estimated 2.5 million people affected. While the numbers of MS patients are strongly increasing, it is unclear how healthcare plans to handle the rising numbers of people affected with MS since there is currently no clear understanding on disease mechanism and thus no effective treatment available that ameliorates the disease. Molecular characterization of innovative prognostic and targeted signaling biomarkers in the pathophysiology is beneficial for the quality of life in MS patients. Furthermore, it also helps to reduce the alarmingly high healthcare costs, caused by the side effects of the non-targeted medication. Therefore, I will perform an investigation to a novel therapeutic strategy by making use of extracellular vesicles as a drug delivery tool to cure MS.

Keywords:Multiple sclerosis,, Extracellular vesicles, theragnostics

Disciplines:Cell death, Cell signalling, Epigenetics, Genetics, Intracellular compartments and transport, Molecular diagnostics, Neurological and neuromuscular diseases