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Publication

Lesional cerebellar epilepsy

Journal Contribution - Journal Article

Subtitle:a review of the evidence

Classical teaching in epileptology localizes the origins of focal seizures solely in the cerebral cortex, with only inhibitory effects attributed to subcortical structures. However, electrophysiological and neuroimaging studies over the last decades now provide evidence for an initiation of epileptic seizures within subcortical structures. Intrinsic epileptogenicity of hypothalamic hamartoma has already been established in recognition of subcortical epilepsy, whereas a seizure-generating impact of dysplastic cerebellar lesions remains to be clarified. Herein, we examine the supportive evidence and clinical presentation of cerebellar seizures and review therapy options.

Journal: J Neurol
ISSN: 0340-5354
Issue: 1
Volume: 264
Pages: 1-10
Publication year:2017
Keywords:Cerebellum, Epilepsy, Hamartoma, Seizures, Surgery
Accessibility:Closed