Researcher
Steven Van Laere
- Research Expertise:Translational Cancer Research, particularly involving the study of human material (i.e. blood, tissue and single cells) using high-throughput profiling technologies (next generation sequencing and microarrays), bioinformatics, data integration and systems biology.
- Keywords:SYSTEMS BIOLOGY, MACHINE LEARNING, MONTE CARLO SIMULATIONS, DATA INTEGRATION, Biomedical sciences (incl. biochemistry)
- Disciplines:Scientific computing, Bioinformatics and computational biology, Public health care, Public health services
- Research techniques:Next generation sequencing (RNA and DNA) Microarrays Isolation of nucleic acids Single cell manipulation Bioinformatics and machine learning Systems biology and data integration
- Users of research expertise:Undergraduate students, PhD students, Post-docs and academic staff
Affiliations
- Center for Oncological Research (CORE) (Research group)
Member
From1 Jan 2019 → Today - Molecular Imaging, Pathology, Radiotherapy & Oncology (MIPRO) (Research group)
Member
From1 Oct 2013 → 31 Dec 2018 - Molecular Imaging, Pathology, Radiotherapy & Oncology (MIPRO) (Research group)
Member
From1 Oct 2003 → 30 Sep 2008
Projects
1 - 10 of 16
- Deciphering the Epigenetic Landscapes of Histopathological Growth Patterns in Colorectal Cancer Liver Metastasis.From1 Jan 2024 → TodayFunding: International Cooperation and Mobility
- Understanding the Effects of Heart Failure Treatments on Cancer Growth.From1 Nov 2023 → TodayFunding: FWO fellowships
- Kino2omics integration platform bridging the Genotype and Phenotype gap in medical research.From1 Sep 2022 → 31 Aug 2023Funding: IOF - technology validation in real environment
- Antwerp core facility for bioinformatics (BIOMINA).From1 Jan 2022 → TodayFunding: BOF - research organisations
- Chitinase 3-like 1 as novel immunotherapeutic target in triple-negative breast cancer.From1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Study towards molecular heterogeneity of circulating tumor cells and their representation of metastatic sites in patients with metastatic breast cancer.From1 Oct 2018 → 30 Sep 2021Funding: FWO fellowships
- The role of infiltrating immune cells in the aggresive phenotype of inflammatory breast cancer and possible new (immuno)therapeutic targets.From1 Oct 2018 → 30 Sep 2020Funding: FWO fellowships
- Altered TGFβ signaling in the context of a type 2 immune response is a prerequisite for inflammatory breast cancer dissemination and metastasis.From1 Jan 2017 → 31 Dec 2017Funding: Nonprofit institution or equivalents
- Study towards molecular heterogeneity of circulating tumor cells and their representation of metastatic sites in patients with metastatic breast cancer.From1 Oct 2016 → 3 Apr 2019Funding: FWO fellowships
- The role of infiltrating immune cells in the aggresive phenotype of inflammatory breast cancer and possible new (immuno)therapeutic targets.From1 Oct 2016 → 30 Sep 2018Funding: FWO fellowships
Publications
1 - 10 of 129
- IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts(2024)
Authors: Astrid Van den Eynde, Laura Gehrcken, Tias Verhezen, Ho Wa Lau, Christophe Hermans, Hilde Lambrechts, Tal Flieswasser, Delphine Quatannens, Gils Roex, Karen Zwaenepoel, et al.
Pages: 1 - 19 - Unraveling the biology of inflammatory breast cancer through multi-omics approaches(2023)
Authors: Charlotte Rypens, Steven Van Laere, Luc Dirix
Number of pages: 169 - Maternal embryonic leucine zipper kinase is associated with metastasis in triple-negative breast cancer(2023)
Authors: Xuemei Xie, Gaurav B. Chauhan, Ramakrishna Edupuganti, Takahiro Kogawa, Jihyun Park, Moises Tacam, Alex W. Tan, Mohd Mughees, Fnu Vidhu, Diane D. Liu, et al.
Pages: 1078 - 1092 - Tspan6 stimulates the chemoattractive potential of breast cancer cells for B cells in an EV- and LXR-dependent manner(2023)
Authors: Guerman Molostvov, Mariam Gachechiladze, Abeer M. Shaaban, Steven Hayward, Isaac Dean, Irundika H.K. Dias, Nahla Badr, Irini Danial, Fiyaz Mohammed, Vera Novitskaya, et al.
Pages: 1 - 22 - Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer(2023)
Authors: Maxim Le Compte, Edgar Cardenas, Sofía Peeters, Felicia Rodrigues Fortes, Christophe Hermans, Evelien Smits, Filip Lardon, Timon Vandamme, Abraham Lin, Steve Vanlanduit, et al.
Pages: 1 - 14 - Immunohistochemical characterisation of the immune landscape in primary uveal melanoma and liver metastases(2023)
Authors: Pascale Mariani, Nouritza Torossian, Steven Van Laere, Peter Vermeulen, Leanne de Koning, Sergio Roman-Roman, Olivier Lantz, Manuel Rodrigues, Marc-Henri Stern, Sophie Gardrat, et al.
Pages: 772 - 781 - Comparison of the genomic alterations present in tumor samples from patients with metastatic inflammatory versus non-inflammatory breast cancer reveals AURKA as a potential treatment target(2023)
Authors: François Richard, Maxim De Schepper, Marion Maetens, Sophia Leduc, Edoardo Isnaldi, Tatjana Geukens, Karen Van Baelen, Ha-Linh Nguyen, Peter Vermeulen, Steven Van Laere, et al.
Pages: 476 - 480 - The role of adipose tissue and subsequent liver tissue hypoxia in obesity and early stage metabolic dysfunction associated steatotic liver disease(2023)
Authors: Annelies Van Eyck, Wilhelmus Kwanten, Cédric Peleman, Sanae Makhout, Steven Van Laere, Kim Van Hoorenbeeck, Joris De Man, Benedicte De Winter, Sven Francque, Stijn Verhulst
Pages: 1 - 11 - Escalation of stereotactic ablative radiotherapy as metastasis-directed therapy(2023)
Authors: Carole Mercier, Piet Dirix, Paul Meijnders, Steven Van Laere, Dirk Verellen
Number of pages: 161 - Liquid biopsies in metastatic breast cancer(2023)
Authors: Aaltje Brouwer, Marc Peeters, Steven Van Laere, Luc Dirix, Emma Beddowes
Number of pages: 154
Patents
1 - 2 of 2