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Project
A precision medicine approach for canine degenerative myelopathy combining genetic and epigenetic alterations
This project aims to introduce precision medicine and epigenetics research in the canine neurogenetics field. Practically, canine degenerative myelopathy will be studied with MBD-seq to identify differentially methylated regions associated with disease progression. This will be followed by the writing of a general statistical analysis framework in R that accurately predicts clinical age ofonset for this disorder.
Date:1 Jan 2019 → 31 Dec 2022
Keywords:Precision medicine, (epi)genetics, degenerative myelopathy
Disciplines:Other veterinary sciences not elsewhere classified, Epigenetics, Animal genetics, Neurophysiology, Neurological and neuromuscular diseases, Cognitive aging, Neurocognitive patterns and neural networks, Agricultural, veterinary and food sciences not elsewhere classified, Veterinary genetics, Neuropsychology, Epigenomics