A basic whole-body bioluminescent and fluorescent in vivo imaging system for small laboratory animals

With in vivo optical imaging the distribution and multiplication of viruses, bacteria, stem and tumor cells, as well as the action of genes, nanomedicines and DNA/RNA drugs can be investigated without the need to kill the experimental animals. By using this technique the number of experimental animals can be drastically reduced in preclinical oncological, pharmacological, immunological, virological and bacteriological research.