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Project
Unraveling and targeting microglia-driven glioma invasion.
The project is aimed at 1) deciphering microglia-derived signals that promote glioma invasion using single cell RNA profiling and spatial transcriptomics on murine and human GBM tissue, 2) evaluate the potential implication of microglia-derived lipids in tumor invasion, and 3) therapeutically exploit these targets to guide a clinical trial for GBM patients at UZ Leuven.
Date:1 Jan 2019 → 31 Dec 2022
Keywords:microglia-derived signals, tumor invasion
Disciplines:Cancer biology