Evaluation of post-operative outcomes in orthognathic surgery patients with systemic medical conditions

This thesis has explored the relationship between systemic diseases and orthognathic surgery outcomes through a series of comprehensive studies. Articles 1 and 2 revealed the significant prevalence of systemic diseases among orthognathic surgery patients, providing a foundational understanding of this specific patient population. In Article 3, we conducted a rigorous analysis that highlighted an elevated risk of postoperative infection among patients with rheumatic diseases, even after accounting for factors such as age, gender, and operation time. Article 4 focused on asthmatic patients, uncovering a higher occurrence of open bite relapse compared to their healthy counterparts. Remarkably, while the maxilla displayed relative stability, the mandible tended to regress in these cases. Finally, Article 5 delved into patients with autoimmune diseases, revealing an increased vulnerability to infection with a delayed onset and the presence of neurosensory disturbances. Notably, a significant number of these patients required the removal of osteosynthesis material to address infections and improve neurosensory feedback.