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Researcher
Abhi Singh
- Disciplines:Virology
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From27 Sep 2018 → Today
Projects
1 - 2 of 2
- Dual targeting of nsp12 and nsp15: a powerful concept to suppress coronavirus replication and transcriptionFrom1 Oct 2022 → TodayFunding: IOF - technology concept exploration
- Structure-based drug design targeting Nipah virus RNA polymeraseFrom1 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 11
- Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine(2022)
Authors: Abhi Singh, Dominique Schols, Piet Herdewyn, Christophe Pannecouque, Kalyan Das
- Insights into HIV-1 Reverse Transcriptase (RT) Inhibition and Drug Resistance from Thirty Years of Structural Studies(2022)
Authors: Abhi Singh, Kalyan Das
- Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening(2021)
Authors: Abhi Singh, Kalyan Das
- Exploring the dNTP -binding site of HIV-1 reverse transcriptase for inhibitor design(2021)
Authors: Weijie Gu, Sergio Martinez, Abhi Singh, Jef Rozenski, Dominique Schols, Piet Herdewyn, Kalyan Das, Steven De Jonghe
- Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening.(2021)
Authors: Abhi Singh, Kalyan Das
Pages: 7127 - Talin rod domain-containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation(2021)
Authors: Abhi Singh
- Development of a Novel SPR Assay to Study CXCR4-Ligand Interactions(2020)
Authors: Arnaud Boonen, Abhi Singh, Kalyan Das, Tom Van Loy, Sam Noppen, Dominique Schols
- Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds(2020)
Authors: Abhi Singh
Pages: 3485 - 3507 - Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2)(2019)
Authors: Abhi Singh
Pages: 4013 - 4029 - Structure and N-acetylglucosamine binding of the distal domain of mouse adenovirus 2 fibre(2018)
Authors: Abhi Singh, Thanh H Nguyen, Marton Z Vidovszky, Balazs Harrach, Maria Benko, Alan Kirwan, Lokesh Joshi, Michelle Kilcoyne, M Alvaro Berbis, F Javier Canada, et al.
Pages: 1494 - 1508