< Back to previous page

Publication

Ophthalmological findings in congenital CMV-infection: when to screen, when to treat?

Journal Contribution - Journal Article

Cytomegalovirus (CMV) is the leading cause of known congenital viral infections. Approximately 90% of congenitally infected newborns exhibit no clinical abnormalities at birth. In 5% to 15%, a wide spectrum of clinical signs is present at birth. Ophthalmological signs are seen in a large percentage of symptomatic patients but rarely in otherwise asymptomatic infants. Chorioretinitis, optic atrophy, and cortical visual impairment are the most frequent causes of visual problems in congenitally infected infants. There is no clear consensus in the literature on screening or treatment modalities concerning the ophthalmological aspects of congenital CMV. Further prospective studies are needed to set up guidelines for ophthalmological screening and treatment of infants with congenital CMV.
Journal: Journal of Pediatric Ophthalmology & Strabismus
ISSN: 0191-3913
Issue: 5
Volume: 49
Pages: 274 - 282
Publication year:2012
BOF-keylabel:yes
IOF-keylabel:yes
BOF-publication weight:0.1
CSS-citation score:2
Authors from:Higher Education
Accessibility:Open