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Project
BRAINDRAIN - Exploring the role of aquaporin 4 in clearing toxic protein aggregates from the brain.
The goal of this project is to ehicidate the contribution of AQP4-mediated glymphatic function in AD development and to screen for compounds or conditions that modulate AQP4-driven pathways. To do so, we will develop and exploit innovative cell culture and manipulation techniques and use advanced 3D imaging paradigms to characterize humanized mouse models.
Date:1 Oct 2018 → 30 Sep 2022
Keywords:AQUAPORIN, ALZHEIMER'S DISEASE
Disciplines:Molecular and cell biology not elsewhere classified, Neuroanatomy, Neurological and neuromuscular diseases, Neurophysiology, Neuroimaging
Project type:Collaboration project