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Project

Structure-activity relationship study of cyclopeptide alkaloids as potential new drugs.

The general aim of this project is to combine the LC-MS and LC-NMR platform available in the Laboratory of Pharmacognosy and Pharmaceutical Analysis (Department of Pharmaceutical Sciences, University of Antwerp) for the characterisation of cyclopeptide alkaloids, a promising class of natural products, from selected plant sources, followed by their targeted isolation, andestablishment of structure-activity relationships in several pharmacological models.
Date:1 Oct 2012 →  31 Dec 2012
Keywords:ALKALOIDS, NEW DRUGS
Disciplines:Biological system engineering, Biomaterials engineering, Biomechanical engineering, Medical biotechnology, Other (bio)medical engineering, Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences