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Project
Hyperendemic M. tuberculosis from a hypertemporal genomic perspective (HyperMTB).
The Karonga Prevention Study has collected, cultured and genome sequenced more than 2000 sputum samples from 1995 to 2014. We will apply a range of phylodynamic methods to investigate the evolution of Mycobacterium tuberculosis over this period. This study will investigate factors involved in strain success, outbreak likelihood of strains and the impact of interventions on strain diversity.
Date:1 May 2018 → 30 Apr 2019
Keywords:GENETIC EPIDEMIOLOGY, TUBERCULOSIS
Disciplines:Microbiology, Systems biology, Laboratory medicine