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Project

Fetal cell isolation and characterization for cell-based non-invasive prenatal genetic diagnosis.

Non-invasive access to fetal cells during pregnancies would revolutionize the field of prenatal testing. This study will enable capture of fetal cells from the maternal blood stream that are suitable to perform massively parallel sequencing and genome wide genetic diagnosis.

Date:1 Jan 2017 →  31 Oct 2022
Keywords:rare cell isolation, Liquid biopsy, cell-based NIPT
Disciplines:Clinical genetics and molecular diagnostics, Epigenetics, Molecular and cell biology, Medical epigenomics, Genetics not elsewhere classified, Transcriptomics, Analysis of next-generation sequence data, Laboratory medicine, Medical transcriptomics, Medical systems biology, Genetic predisposition, Genetics, Medical genomics, Population, ecological and evolutionary genetics, Metagenomics, Medical metagenomics, Systems biology, Genome structure and regulation, Biomarker discovery and evaluation not elsewhere classified, Epigenomics, Genomics, Single-cell data analysis, Quantitative genetics