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Project

Assessing the link between Alzheimer's disease and atherosclerosis in the APP23 x ApoE knockout mouse model.

Besides being pivotal Alzheimer's disease proces, amyloid precursor protein is presumed to play a crucial rol in atherosclerosis as well. The link between both disorders will be studied in a cross model based on the APP23 transgenic amyloidosis Alzheimer's model and the atherosclerosis-prone ApoE knockout model at the behavioural, biochemical, morphological and histopathological level.
Date:1 Feb 2009 →  31 Dec 2010
Keywords:MOUSE MODELS, ALZHEIMER'S DISEASE, ATHEROSCLEROSIS, AMYLOID PRECURSOR PROTEIN
Disciplines:Laboratory medicine, Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing