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Project
The direct effects of elevated serum free fatty acid concentrations on the viability of ovarian follicles and the oocyte's developmental capacity.
Previous research work revealed that metabolic changes, associated with the growing incidence of obese individuals and diabetics, might have harmful repercussions for the reproductive outcome. The consequences of hyperglycemia, due to obesity and diabetes, have already been investigated thoroughly in rats and mice. This research project rather involves another feature of these metabolic pathologies: the high free fatty acid concentrations in blood. The interest of the human assisted reproduction society in a bovine model to assess the influence of free fatty acids on the oocytes developmental competence, on the viability and function of the granulosa cells and the inquisitiveness to the underlying mechanism of these potential effects, imposes us to further research.
Date:1 Oct 2011 → 6 Oct 2013
Keywords:REPRODUCTION PHYSIOLOGY, PATHOPHYSIOLOGY
Disciplines:Animal biology, General biology, Genetics, Gynaecology and obstetrics, Molecular and cell biology, Morphological sciences, Veterinary medicine