Principle component analysis (PCA) of complex data generated by chromatographic and spectroscopic analysis of biological mixtures.

There is a never-ending search for novel molecules with superior pharmaceutical properties. Via an IWT-SBO project the production of novel molecules in plants, through use of combinatorial biosynthesis, was started . Because of the high amount of constructs that will be created to screen for new metabolites, a statistical approach will be necessary. To support the statistics of these analyses principle component analysis (PCA) will be necessary.

Keywords:SAPONINS, METABOLOMICS, PRINCIPAL COMPONENT ANALYSIS, LC-MS

Disciplines:Scientific computing, Analytical chemistry, Bioinformatics and computational biology, Public health care, Public health services, Pharmaceutical analysis and quality assurance