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Project
The link between hypoxia and progenitor cells during liver carcinogenesis (FWOAL689)
Every year nearly half a million patients are diagnosed with a primary liver tumor. In this research we would like to assess the influence of hypoxia (low oxygen levels) and reduced oxygen sensing on liver stem cells and how this could influence tumor development.
Date:1 Jan 2013 → 31 Dec 2016
Keywords:Fibrosis, Hepatic Stellate Cells, Histon (de)acetylation, Stellate cell activation, Liver Cell Transplantation, Liver Sinusoidal Cells, Portal hypertension, Sinusoidal Cells, cirrhosis, Cytoskeleton, Cell Biology, Fat-Storing Cells, NASH / NAFLD, Intermediate Filaments, liver stem / progenitor cells, autophagy, Flow Cytometry, Metabolic Syndrome
Disciplines:Cancer therapy, Morphological sciences, Immunology, Oncology, Multimedia processing