Study of the role of immune cells in RSV infections.

RSV is worldwide an important cause of medical relevant lung infections, which can lead to life-threatening bronchiolitis in children and elderly. Besides the acute pathology, there is a link between severe bronchiolitis and chronic respiratory problems. The pathology is induced by both the cytopathic effect of the infection as well as the RSV induced immunomodulation. Since immune cells are an important component, we will study the interaction of RSV with these cells and try to modulate their activities.

Keywords:RESPIRATORY SYNCYTIAL VIRUS (RSV), MACROPHAGES, RECEPTORS

Disciplines:Microbiology, Systems biology, Immunology, Laboratory medicine