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Project

Role of cMyc-PP2A negative feedback control in hepatocyte growth, liver regeneration and hepatocellular carcinoma development

This project investigates the tumor suppressive role of a specific PP2A complex in the liver, and provides proof-of-principle of how reconstitution of this function may contribute to improved liver cancer therapies.
Date:1 Jan 2016 →  31 Dec 2019
Keywords:hepatocyte growth, negative feedback control, cMyc-PP2A, liver regeneration, hepatocellular carcinoma development
Disciplines:Morphological sciences, Oncology