Synthesis and biological evaluation of albomycin and aminoacyl sulfonamide analogues as potential aaRS inhibitors.

This project focuses on the synthesis and development of new antibiotic scaffolds, which is highly desired in view of the continuous increase in resistance to our present armamentarium of antibiotics.

Keywords:aaRS inhibitors., aminoacylsulfonamide analogues, biological evaluation, Synthesis

Disciplines:Laboratory medicine, Medical systems biology, Medicinal chemistry