De ontwikkeling van een monitoring systeem voor het opvolgen van celpopulaties in real-time.

Monitoring real-time cell behavior is an important analytical research method that can be applied in a wide field of biotechnological domains, such as diagnostic research, drug screening and regenerative medicine. The current techniques for studying cell behavior are mostly limited to end point analysis and are almost all exclusively aimed toward biologicalaspects. The aim of this research is to develop an intelligent monitoring system which is able to follow and control the dynamics of cell populations in an advanced, quantitative and non-invasive manner. In a first stage we will implement sensor technology to monitor multiple biologicalparameters of the cell population simultaneously and to combine these with the analysis of real-time imaging. The generated data will be used as input to develop a data based modeling algorithm, which will be able to describe the behavior of the cell population both temporal and spatial. This unique approach allows the use of global environment data to non-invasively study and predict cell behavior in populations in a more complex environment. </>

Keywords:celpopulaties, real-time., monitoring systeem

Disciplines:Control systems, robotics and automation, Design theories and methods, Mechatronics and robotics, Computer theory, Agriculture, land and farm management, Biotechnology for agriculture, forestry, fisheries and allied sciences, Fisheries sciences

Project type:PhD project