Researcher
Ilse DEWACHTER
- Keywords (Hasselt University):Biomedical sciences (incl. biochemistry)
- Keywords (Hasselt University):Biomedical sciences (incl. biochemistry)
- Disciplines (Hasselt University):Immunology not elsewhere classified, General and logistic services
- Disciplines (Hasselt University):Inflammation, Innate immunity, Immunology not elsewhere classified, Cognitive neuroscience, Neuroanatomy, Neurological and neuromuscular diseases, Neurosciences not elsewhere classified, Protein diagnostics, Cell death, Cell signalling, Cellular interactions and extracellular matrix, Cytoskeleton
- See also: Sarah VANHERLE (Hasselt University)
Affiliations
- Neurosciences (Department)
Member
From1 Jan 2020 → Today - Neurosciences (Research group)
Member
From1 Jan 2020 → Today - Neurosciences (Research group)
Responsible
From1 Jan 2020 → Today - Biomedical Research Institute (Research institute)
Member
From1 Jan 2017 → Today - Faculty of Medicine and Life Sciences (Faculty)
Member
From1 Jan 2017 → Today - Neurosciences (Research group)
Member
From1 Jan 2020 → Today - Neurosciences (Department)
Member
From1 Jan 2020 → Today - Biomedical Research Institute (Research institute)
Member
From3 Jun 2019 → Today - Faculty of Medicine and Life Sciences (Faculty)
Member
From3 Jun 2019 → Today - Physiology - Biochemistry - Immunology (Department)
Member
From16 Aug 2019 → 31 Dec 2019 - Immunology - Biochemistry (Research group)
Member
From3 Jun 2019 → 31 Dec 2019 - Physics (Department)
Member
From3 Jun 2019 → 15 Aug 2019 - Physiology - Biochemistry - Immunology (Department)
Member
From1 Jan 2017 → 31 Dec 2019 - Physiology (Research group)
Member
From1 Jan 2017 → 31 Dec 2019
Projects
1 - 10 of 12
- Impact of volume versus intensity of exercise therapy on the brain in T2DM.From1 Jan 2023 → TodayFunding: BOF - doctoral mandates
- Halting amyloid induced tau pathology, by modifying ApoE-dependent lipid homeostasis: checking the FACTS on FATS as a modifiable target for preventing AD.From1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Personalized prevention and halting of Alzheimer's Disease progression along the ATN axis: Targeting ApoE, neuroinflammation and lipid metabolismFrom8 Jul 2022 → TodayFunding: BOF - Methusalem
- MULTISCALE - The UHasselt MultiScale Optical Imaging Core: Infrastructure for nano- to centimeter length scale microscopy and analysis of 'big' 4D datasetsFrom1 May 2022 → TodayFunding: Industrial enterprises, FWO Large scale research infrastructure, Foreign public sponsor, Own budget, for example: patrimony, inscription fees, gifts
- MULTISCALE - Infrastructure for nano- to centimeter length scale microscopy and big data analysis of optical imaging dataFrom1 Apr 2022 → TodayFunding: BOF - scientific equipment program
- The role of APOE in Tau-pathology and neurodegeneration downstream of Aβ pathology: Exploiting a human protective APOE3 (R136S) mutation to develop novel therapeutic strategies for Alzheimer's diseaseFrom1 Jan 2021 → 31 Dec 2023Funding: Foundations, funds and other with scientific goal
- Inflammasome activation in TH lymphocytes, induced by mitochondrial impairment, causes local tissue damage in the brain of multiple sclerosis patients.From1 Nov 2020 → TodayFunding: BOF - doctoral mandates
- The role of ApoE-mediated neuroinflammation in the progression along the pathogenetic axis in AD.From1 Oct 2020 → 30 Sep 2023Funding: FWO senior postdoctoral fellowship
- Single-molecule structural investigations of tau proteinFrom1 Aug 2020 → TodayFunding: BOF - doctoral mandates
- Inflammasome activation in T lymphocytes: a new player in the complex immune response in multiple sclerosis patientsFrom1 Jan 2020 → 31 Dec 2022Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 23
- Hallmarks of neurodegenerative diseases(2023)
Authors: David WILSON, Mark R. Cookson, Ludo Van Den Bosch, Henrik Zetterberg, David M. Holtzman, Ilse DEWACHTER
Pages: 693 - 714 - Dopamine-mediated striatal activity and function is enhanced in GlyR alpha 2 knockout animals(2023)
Authors: Jens DEVOGHT, Joris COMHAIR, Giovanni MORELLI, Jean-Michel RIGO, Rudi D'Hooge, Chadi Touma, Rupert Palme, Ilse DEWACHTER, Martin VAN DE VEN, Robert J. Harvey, et al.
- Targeting Alzheimer’s Disease progression along the Amyloid/ Tau/Neurodegeneration axis: NLRP3-inflammasome-based halting and early prevention strategies(2023)
Authors: Pablo BOTELLA LUCENA, Ilse DEWACHTER
Number of pages: 220 - The role of microglia in preclinical models recapitulating the key ATN pathologies of Alzheimer's Disease(2022)
Authors: Chritica LODDER, Ilse DEWACHTER
Number of pages: 223 - Blood-based A beta 42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention(2022)
Authors: Pablo BOTELLA LUCENA, Sarah VANHERLE, Chritica LODDER, Manu GUTIERREZ DE RAVE, Ilie Cosmin STANCU, Ivo LAMBRICHTS, Riet Vangheluwe, Rose BRUFFAERTS, Ilse DEWACHTER
Pages: 489 - 508 - CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia(2021)
Authors: Chritica LODDER, I Scheyltjens, Ilie Cosmin STANCU, Pablo BOTELLA LUCENA, Manu GUTIERREZ DE RAVE, Sarah VANHERLE, Tim VANMIERLO, Niels CREMERS, Hannah VANRUSSELT, Bert BRONE, et al.
- Disrupted-In-Schizophrenia 1 controls microglial movement and phagocytosis(2021)
Authors: Sofie KESSELS, Lisa BERDEN, Yeranddy AGUIAR ALPIZAR, Jolien BEEKEN, Chloe TRIPPAERS, Ben ROMBAUT, K Ishizuka, L Nguyen, J Antel, L Healy, et al.
Pages: E118 - Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study(2019)
Authors: Bernard J. Hanseeuw, Rebecca A. Betensky, Heidi I. L. Jacobs, Aaron P. Schultz, Jorge Sepulcre, J. Alex Becker, Danielle M. Orozco Cosio, Michelle Farrell, Yakeel T. Quiroz, Elizabeth C. Mormino, et al.
Pages: 915 - 924 - Sargassum fusiforme improves memory and reduces amyloid plaque pathology in an Alzheimer's disease mouse model(2019)
Authors: Jeroen BOGIE, Cindy HOEKS, Melissa SCHEPERS, Assia TIANE, Ann CUYPERS, F. Leijten, Y. Chintapakorn, T. Suttyut, S. Pornpakakul, D. Struik, et al.
Pages: E430 - E430 - Sex-regulated gene dosage effect of PPARα on synaptic plasticity(2019)
Authors: Nathalie Pierrot, Laurence Ris, Ilie Cosmin STANCU, Anna Doshina, Floriane Ribeiro, Donatienne Tyteca, Eric Baugé, Fanny Lalloyer, Liza Malong, Olivier Schakman, et al.