Investigating microbial therapies to combat gut microbiome dysbiosis during pelvic irradiation.

Pelvic irradiation is a common treatment strategy for various cancers such as colon cancer and cervical cancer. High irradiation doses result in many side effects such as diarrhea, inflammation and microbiome dysbiosis. In this project, the effect of Arthrospira on many of these side effects will be explored at a molecular level, in a mouse model developed at SCK. These effects will be compared with the model probiotic Lactobacillus rhamnosus GG. Growth of Arthrospira will also be optimized.

Keywords:MICROBIOLOGY

Disciplines:Microbiology, Systems biology, Laboratory medicine

Project type:Collaboration project