Researcher
Ann Massie
- Keywords:Pharmacy and pharmacology
- Disciplines:Biogerontology, Inflammation, Cognitive neuroscience, Neurophysiology
Affiliations
- Neuro-Aging & Viro-Immunotherapy (Research group)
Responsible
From18 Nov 2020 → Today - Pharmaceutical and Pharmacological Sciences (Department)
Member
From1 Jan 2022 → Today - Pharmaceutical and Pharmacological Sciences (Department)
Member
From8 Apr 2019 → Today - Pharmaceutical and Pharmacological Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Pharmaceutical Biotechnology and Molecular Biology (Department)
Member
From1 Oct 2011 → 31 Dec 2013 - Pharmaceutical Chemistry, Drug Analysis and Drug Information (Department)
Member
From10 Nov 2004 → 30 Sep 2011
Infrastructure
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Projects
1 - 10 of 13
- Targeting system xc- to simultaneously tackle the metabolic and neurological comorbidities of diet-induced obesityFrom1 Nov 2023 → TodayFunding: FWO fellowships
- System xc- as metabolic regulator in the aging brainFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- SRP-Onderzoekszwaartepunt: Translating the biology of cognitive function to improve diagnosis and treatment of brain disordersFrom1 Oct 2022 → TodayFunding: BOF - projects
- Seahorse platform: the Agilent Seahorse Flux Analyser with integrated normalization systemFrom1 May 2020 → TodayFunding: Hercules - Small and Medium size research infrastructure
- System xc- as a novel therapeutic target to limit neurodegeneration in Parkinson’s diseaseFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- Strategic Research Programme: Understanding reciprocal neuron-glia interactions in health and disease as a basis for innovative neurological and neuropsychopharmacological therapiesFrom1 Oct 2017 → TodayFunding: University - Project driven research
- SRP (Groeiers): Unveiling the role of the cystine/glutamate antiporter (system xc-) in temporal lobe epilepsy, major depression and Parkinson’s diseaseFrom1 Mar 2014 → 28 Feb 2019Funding: BOF - Concerted Research Project from 1994
- Validation of the role of the cystine/glutamate antiporter or system xc- in disorders of the visual systemFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- Major Depression - Cystine/glutamate antiporterFrom1 Jan 2013 → 31 Dec 2016Funding: IWT personal funding - strategic basic research grants
- Unravelling the role of system xc- in epileptogenesisFrom1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 48
- Compartmentalized role of xCT in supporting pancreatic tumor growth, inflammation and mood disturbance in mice(2024)
Authors: Olaya Lara, Pauline Janssen, Marco Mambretti, Laura De Pauw, Gamze Ates, Liselotte Mackens, Jolien De Munck, J Walckiers, Zhaolong Pan, Pauline Beckers, et al.
Pages: 275-286 - Characterization of the long-term effects of lethal total body irradiation followed by bone marrow transplantation on the brain of C57BL/6 mice(2024)
Authors: Pauline Janssen, Laura De Pauw, Marco Mambretti, Olaya Lara, J Walckiers, Liselotte Mackens, Ilse Rooman, B. Guillaume, Mark De Ridder, Gamze Ates, et al.
Pages: 385-398 - Pancreatic acinar cell fate relies on system xC- to prevent ferroptosis during stress(2023)
Authors: Zhaolong Pan, Jan-Lars Van den Bossche, Eva Rodriguez Aznar, Pauline Janssen, Olaya Lara, Gamze Ates, Ann Massie, Diedert Luc De Paep, I Houbracken, Marco Mambretti, et al.
- Effects of lactate, super-GDF9 and low oxygen tension during biphasic in vitro maturation on the bioenergetic profiles of mouse cumulus-oocyte-complex(2023)
Authors: Nazli Akin, Gamze Ates, Lucia von Mengden, Anamaria-Cristina Herta, Cecilia Meriggioli, Katy Billooye, William A Stocker, Brecht Ghesquiere, Craig A Harrison, Wilfried Cools, et al.
Pages: 432-449 - AMPKα1 Deficiency in Astrocytes from a Rat Model of ALS Is Associated with an Altered Metabolic Resilience(2023)
Authors: Inês Belo do Nascimento, Gamze Ates, Nathalie Desmet, Pauline Beckers, Ann Massie, Emmanuel Hermans
- Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis(2023)
Authors: Arne Van der Vreken, Inge Oudaert, Gamze Ates, Sylvia Faict, Philip Vlummens, Hatice Satilmis, Rong Fan, Anke Maes, Ann Massie, Kim De Veirman, et al.
Pages: 112-123 - Targeting the β2 -adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism(2023)
Authors: Hatice Satilmis, Emma Verheye, Philip Vlummens, Inge Oudaert, Niels Vandewalle, Rong Fan, Jennifer M Knight, Nathan De Beule, Gamze Ates, Ann Massie, et al.
Pages: 69–80 - Structural investigation of human cystine/glutamate antiporter system xc− (Sxc−) using homology modeling and molecular dynamics(2022)
Authors: Dieu Hang Tran, Minh Hung Huynh, Pauline Beckers, Nathalie Desmet, Mohamed Lamrani, Ann Massie, Emmanuel Hermans, Kenno Vanommeslaeghe
- Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation(2022)
Authors: Karen De Vlaminck, Hannah Van Hove, Daliya Kancheva, Isabelle Scheyltjens, Ana Rita Pombo Antunes, Jonathan Bastos, Monica Vara-Perez, Leen Ali, Myrthe Mampay, Lauren Deneyer, et al.
Pages: 2085-2102 - Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes(2022)
Authors: Sophia Maschalidi, Parul Mehrotra, Burcu Nur Keçeli, Hannah K L De Cleene, Kim Lecomte, Renée Van der Cruyssen, Pauline Janssen, Jonathan Pinney, Geert Van Loo, Dirk Elewaut, et al.
Pages: 776-784
Linked dataset
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