Researcher
Carl De Trez
- Keywords:Applied biological sciences, biotechnology
- Disciplines:Infectious diseases, Inflammation, Adaptive immunology
Affiliations
- Cellular and Molecular Immunology (Research group)
Member
From1 Jan 2008 → Today - Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → Today - Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → Today - Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → 31 Aug 2023 - Department of Bio-engineering Sciences (Department)
Member
From1 Jan 2016 → 20 Oct 2022 - Structural Biology Brussels (Department)
Member
From1 Jan 2016 → 31 Oct 2017 - Department of Bio-engineering Sciences (Department)
Member
From15 Jan 2011 → 20 Oct 2022
Projects
1 - 2 of 2
- SRP-Groeifinanciering: Unravelling the host-parasite interactions that result in B cell destruction during trypanosomosis and development of novel intervention strategies focusing on diagnosis and anti B cell cancer therapyFrom1 Mar 2019 → TodayFunding: BOF - projects
- Molecular and cellular characterization of the mechanisms implicated in intestinal B cell depletion following Trypanosoma brucei infection and its impact on host survival.From1 Jan 2013 → 31 Dec 2013Funding: FWO research grant KAN
Publications
1 - 10 of 45
- Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids(2024)
Authors: Benoit Stijlemans, Patrick De Baetselier, Inge Van Molle, Laurence Lecordier, Erika Hendrickx, Ema Romao, Cécile Vincke, Wendy Baetens, Steve Schoonooghe, Gholamreza Hassanzadeh Ghassabeh, et al.
- The Role of MIF and IL-10 as Molecular Yin-Yang in the Modulation of the Host Immune Microenvironment During Infections(2022)
Authors: Benoit Stijlemans, Maxime Schoovaerts, Patrick De Baetselier, Stefan Magez, Carl De Trez
- Miltefosine enhances infectivity of a miltefosine-resistant Leishmania infantum strain by attenuating its innate immune recognition(2021)
Authors: Dimitri Bulté, Lieselotte Van Bockstal, Laura Dirkx, Magali Van den Kerkhof, Carl De Trez, Jean-Pierre Timmermans, Sarah Hendrickx, Louis Maes, Guy Caljon
- ILC3s control splenic cDC homeostasis via lymphotoxin signaling.(2021)
Authors: Matthias Vanderkerken, Antonio Baptista, Marco De Giovanni, Satoshi Fukuyama, Robin Browaeys, Charlotte L. Scott, Paula S Norris, Gérard Eberl, James P. Di Santo, Eric Vivier, et al.
- USP13 controls the stability of Aurora B impacting progression through the cell cycle(2020)
Authors: Mara Esposito, H Begum Akman, Philippe Giron, Maria De Los Angeles Ceregido Perez, Rogier Schepers, Luis Carlos Ramos Paez, Esther La Monaca, Jacques De Grève, Olivier Coux, Carl De Trez, et al.
Pages: 6009-6023 - A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Trypanosoma brucei Infection.(2020)
Authors: Carl De Trez, Benoit Stijlemans, Viki Bockstal, Jennifer Cnops, Hannelie Korf, Jacques Van Snick, Guy Caljon, Eric Muraille, Ian R Humphreys, Louis Boon, et al.
Pages: 1085 - T. brucei infections abrogate diverse plasma cell-mediated effector B cell responses, independently of their specificity, affinity and host genetic background.(2020)
Authors: Carl De Trez, Shahid Khan, Stefan Magez
Pages: 1-14 - Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection.(2020)
Authors: Stefan Magez, Benoit Stijlemans, Hannelie Korf, Patrick De Baetselier, Jo A Van Ginderachter, Carl De Trez
- Trypanosoma brucei brucei causes a rapid and persistent influx of neutrophils in the spleen of infected mice.(2019)
Authors: Stefan Magez, Carl De Trez
- Neutrophils enhance early Trypanosoma brucei infection onset(2018)
Authors: Guy Caljon, Dorien Mabille, Carl De Trez, Massimiliano Mazzone, Fabienne Tacchini-Cottier, Marie Malissen, Jo A Van Ginderachter, Stefan Magez, Patrick De Baetselier, Jan Van Den Abbeele, et al.