Researcher
Elien GRAJCHEN
- Keywords:Biomedical sciences (incl. biochemistry)
- Disciplines:Adaptive immunology, Autoimmunity, Inflammation, Innate immunity, Cell signalling
Affiliations
- Immunology & Infection (Department)
Member
From1 Jan 2020 → 31 Dec 2021 - Immunology & Infection (Research group)
Member
From1 Jan 2020 → 31 Dec 2021 - Biomedical Research Institute (Research institute)
Member
From16 Jul 2016 → 31 Dec 2021 - Faculty of Medicine and Life Sciences (Faculty)
Member
From16 Jul 2016 → 31 Dec 2021 - Physiology - Biochemistry - Immunology (Department)
Member
From16 Jul 2016 → 31 Dec 2019 - Immunology - Biochemistry (Research group)
Member
From16 Jul 2016 → 31 Dec 2019
Projects
1 - 2 of 2
- Boosting lesion repair in multiple sclerosis by preventing lipid overload in phagocytes / Short title: Fatty acids control foamy phagocyte functionFrom1 Jan 2019 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
- Fatty acid metabolism in control of the phenotype in phagocytes in MS lesionsFrom1 Oct 2016 → 30 Sep 2020Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 10
- Phloretin enhances remyelination by stimulating OPC differentiation(2021)
Authors: Tess DIERCKX, Sam VANHERLE, Mansour HAIDAR, Elien GRAJCHEN, Pascal GERVOIS, D Bylemans, A Voet, T Nguyen, Jeroen BOGIE, Jerome HENDRIKS
Pages: E530 - Fatty Acid Metabolism in Control of Immune Cell Function in Multiple Sclerosis(2021)
Authors: Elien GRAJCHEN, Jerome HENDRIKS
Number of pages: 234 - Phloretin suppresses neuroinflammation by autophagy-mediated Nrf2 activation in macrophages(2021)
Authors: Tess DIERCKX, Mansour HAIDAR, Elien GRAJCHEN, Elien WOUTERS, Sam VANHERLE, Melanie LOIX, Annick Boeykens, Dany Bylemans, Kevin Hardonniere, Saadia Kerdine-Romer, et al.
- CNS delivery of anti-CD52 antibodies modestly reduces disease severity in an animal model for multiple sclerosis(2020)
Authors: Jeroen BOGIE, Elien GRAJCHEN, Elien WOUTERS, Bieke BROUX, Piet STINISSEN, Bart VAN WIJMEERSCH, Jerome HENDRIKS
- Altered PPARĪ³ Expression Promotes Myelin-Induced Foam Cell Formation in Macrophages in Multiple Sclerosis(2020)
Authors: Elien WOUTERS, Elien GRAJCHEN, Winde JORISSEN, Tess DIERCKX, Suzan WETZELS, Melanie LOIX, Marie-Paule TULLENERS, Bart Staels, Piet STINISSEN, Mansour HAIDAR, et al.
- CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation(2020)
Authors: Elien GRAJCHEN, Elien WOUTERS, van de, Britt Haterd, Mansour HAIDAR, K Hardonniere, Tess DIERCKX, Jana VAN BROECKHOVEN, Celine ERENS, S Kerdine-Romer, Sven HENDRIX, et al.
- Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain(2020)
Authors: Jeroen BOGIE, Elien GRAJCHEN, Elien WOUTERS, Aida GARCIA CORRALES, Tess DIERCKX, Sam VANHERLE, Jo MAILLEUX, Pascal GERVOIS, Esther WOLFS, Jonas Dehairs, et al.
- Fatty acid desaturation impairs the reparative features of phagocytes in the central nervous system(2019)
Authors: Jeroen BOGIE, Elien GRAJCHEN, Elien WOUTERS, Aida GARCIA CORRALES, Tess DIERCKX, Mansour HAIDAR, Jo MAILLEUX, Pascal GERVOIS, Esther WOLFS, J. Dehairs, et al.
Pages: 676 - 677 - The physiology of foamy phagocytes in multiple sclerosis(2018)
Authors: Elien GRAJCHEN, Jerome HENDRIKS, Jeroen BOGIE
- Scavenger receptor collectin placenta 1 is a novel receptor 1 involved in the uptake of myelin by phagocytes(2017)
Authors: Jeroen BOGIE, Jo MAILLEUX, Elien WOUTERS, Winde JORISSEN, Elien GRAJCHEN, Jasmine VANMOL, Kristiaan WOUTERS, Niels HELLINGS, Jack Van Horsen, Tim VANMIERLO, et al.
Pages: 1 - 9