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Project

NEURO.GSK3: GSK3 in neuronal plasticity and neurodegeneration: basic mechanisms and pre-clinical assessment.

Knowledge of function and role, resp. in neuro-physiology and in neuro-pathology, of the GSK3 kinases will be translated into compounds and tools to regulate, in vivo, the activity of GSK3 kinases and the pathways that they participate in healthy and in diseased neurons. The activities will help to generate and validate specific and safe therapeutical compounds and identify additional targets - all needed to help curb neurodegeneration in patients suffering from Alzheimer's dementia.
Date:1 Oct 2008 →  31 Dec 2011
Keywords:GSK3
Disciplines:Genetics, Systems biology, Molecular and cell biology