Researcher
Giel Tanghe
- Disciplines:Biophysics, Molecular and cell biology, Laboratory medicine, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From1 Sep 2011 → 7 Aug 2022
Projects
1 - 1 of 1
- Identification of RIPK4-dependent signalling pathways and the role of RIPK4 in skin homeostasis and diseaseFrom1 Oct 2013 → 30 Sep 2017Funding: FWO fellowships, BOF - Other initiatives
Publications
1 - 9 of 9
- Functions of the RIP kinase family members in the skin(2023)
Authors: Corinne Urwyler, Giel Tanghe, Michael Devos, Paco Hulpiau, Yvan Saeys, Wim Declercq
- Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation(2020)
Authors: Michael Devos, Giel Tanghe, Barbara Gilbert, Evelien Dierick, Maud Verheirstraeten, Josephine Nemegeer, Richard de Reuver, Sylvie Lefebvre, Jolien De Munck, Jan Rehwinkel, et al.
- Keratinocyte-Specific Ablation of RIPK4 Allows Epidermal Cornification but Impairs Skin Barrier Formation(2018)
Authors: Corinne Urwyler, Giel Tanghe, Kirsten Leurs, Barbara Gilbert, Michiel De Bruyne, Saskia Lippens, Sona Bartunkova, Philippe De Groote, Carien Niessen, Marek Haftek, et al.
Pages: 1268 - 1278 - Mechanistic insights into the regulation of RIPK4 and its function in skin homeostasis and pathology(2018)
Authors: Giel Tanghe
- RIPK4 activity in keratinocytes is controlled by the SCFβ-TrCP ubiquitin ligase to maintain cortical actin organization(2018)
Authors: Giel Tanghe, Corinne Urwyler, Philippe De Groote, Emmanuel Dejardin, Pieter-Jan De Bock, Peter Vandenabeele
Pages: 2827 - 2841 - Co-activation of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ in murine skin prevents worsening of atopic march(2018)
Authors: Julie Deckers, Nadia Bougarne, Viacheslav Mylka, Sofie Desmet, Astrid Luypaert, Michael Devos, Giel Tanghe, Justine Van Moorleghem, Manon Vanheerswynghels, Lode De Cauwer, et al.
Pages: 1360 - 1370 - Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells(2016)
Authors: Philippe De Groote, Sasker Grootjans, Saskia Lippens, Kirsten Leurs, Irene Kahr, Giel Tanghe, Inge Bruggeman, Wouter De Schamphelaire, Corinne Urwyler, Peter Vandenabeele, et al.
Pages: 252 - 259 - A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes(2015)
Authors: Philippe De Groote, Hong Tran Thi, Mathias Fransen, Giel Tanghe, Corinne Urwyler, Bram De Craene, Kirsten Leurs, Barbara Gilbert, Griet Van Imschoot, Chris Guerin, et al.
Pages: 1012 - 1024 - Lineage tracing mediated by Cre-recombinase activity(2015)
Authors: Susanne Vorhagen, Joanna Jackow, Simona Georgina Mohor, Giel Tanghe, Luna Tanrikulu, Claudia Skazik-Vogt, Frederik Tellkamp