Researcher
Steven De Munck
- Disciplines:Biophysics, Molecular and cell biology, Medical biochemistry and metabolism, Laboratory medicine, Microbiology, Systems biology, Plant biology, Biochemistry and metabolism, Medicinal and biomolecular chemistry
Affiliations
- Department of Biochemistry and microbiology (Department)
Member
From23 Sep 2014 → Today
Projects
1 - 1 of 1
- Structural and biophysical characterization of extracellular assemblies of the anaplastic lymphoma kinase receptorFrom1 Jan 2015 → 31 Dec 2018Funding: IWT personal funding - strategic basic research grants, IWT personal funding - specialisation scholarships
Publications
1 - 10 of 11
- Improving de novo protein binder design with deep learning(2023)
Authors: Nathaniel R. Bennett, Brian Coventry, Inna Goreshnik, Buwei Huang, Aza Allen, Dionne Vafeados, Ying Po Peng, Justas Dauparas, Minkyung Baek, Lance Stewart, et al.
- Structural basis of cytokine-mediated activation of ALK family receptors(2021)
Authors: Steven De Munck, Mathias Provost, Michiko Kurikawa, Ikuko Omori, Junko Mukohyama, Jan Félix, Yehudi Bloch, Omar Abdel-Wahab, J. Fernando Bazan, Akihide Yoshimi, et al.
Pages: 143 - 147 - Structure and mechanism of cytokine mediated activation of ALK family receptor tyrosine kinases(2021)
Authors: Steven De Munck
- Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents(2020)
Authors: Yanlin Jian, Romain Merceron, Steven De Munck, He Eun Forbes, Fabian Hulpia, Martijn Risseeuw, Kristof Van Hecke, Savvas Savvides, Hélène Munier-Lehmann, Helena I. M. Boshoff
- Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis(2020)
Authors: Sandra Kozak, Yehudi Bloch, Steven De Munck, Aleksandra Mikula, Isabel Bento, Savvas Savvides, Rob Meijers
Pages: 1244 - 1255 - Structure and assembly mechanism of the signaling complex mediated by human CSF-1 (vol 23, pg 1621, 2015)(2020)
Authors: Jan Félix, Steven De Munck, Kenneth Verstraete, Leander Meuris, Jonathan Elegheert, Savvas Savvides
- Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms(2019)
Authors: Benjamin H Durham, Estibaliz Lopez Rodrigo, Jennifer Picarsic, David Abramson, Veronica Rotemberg, Steven De Munck, Erwin Pannecoucke, Sydney X Lu, Alessandro Pastore, Akihide Yoshimi, et al.
Pages: 1839 - 1842 - Disruption of endocytosis through chemical inhibition of clathrin heavy chain function(2019)
Authors: Wim Dejonghe, Isha Sharma, Bram Denoo, Steven De Munck, Qing Lu, Kiril Mishev, Haydar Bulut, Evelien Mylle, Riet De Rycke, Mina Vasileva, et al.
Pages: 641 - 649 - Nonselective chemical inhibition of Sec7 domain-containing ARF GTPase exchange factors(2018)
Authors: Kiril Mishev, Qing Lu, Bram Denoo, Francois Peurois, Wim Dejonghe, Jan Hullaert, Sjef Boeren, Marine Bretou, Steven De Munck, Isha Sharma, et al.
Pages: 2573 - 2593 - Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF(2016)
Authors: Jan Félix, Eaazhisai Kandiah, Steven De Munck, Yehudi Bloch, Gydo CP van Zundert, Kris Pauwels, Katka Novanska, Randy J Read, Alexandre MJJ Bonvin, Bjorn Vergauwen, et al.