Researcher
Dorien Van Lysebetten
- Disciplines:Macromolecular and materials chemistry not elsewhere classified
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Mar 2019 → 31 Jan 2020 - Department of Organic and Macromolecular Chemistry (Department)
Member
From1 Oct 2014 → 22 Sep 2019
Projects
1 - 1 of 1
- Design and synthesis of cyclic peptides with improved therapeutic potential by molecular grafting of peptide loop sequences onto steroid scaffoldsFrom1 Oct 2015 → 28 Feb 2019Funding: BOF - Doctoral projects
Publications
1 - 9 of 9
- Lipid-polyglutamate nanoparticle vaccine platform(2021)
Authors: Dorien Van Lysebetten, Alessio Malfanti, Kim Deswarte, Kaloian Koynov, Bianka Golba, Tingting Ye, Sabah Kasmi, Alexander Lamoot, Yong Chen, Simon Van Herck, et al.
Pages: 6011 - 6022 - Design and synthesis of cyclic peptide-bile acid conjugates for improving the therapeutic potential of peptide drugs(2019)
Authors: Dorien Van Lysebetten
- NMR structure of μ-conotoxin GIIIC : leucine 18 induces local repacking of the N-terminus resulting in reduced NaV channel potency(2018)
Authors: Peta J Harvey, Nyoman D Kurniawan, Rocio K Finol-Urdaneta, Jeffrey R McArthur, Dorien Van Lysebetten, Thomas S Dash, Justine M Hill, David J Adams, Thomas Durek, David J Craik
- A thiolactone strategy for straightforward synthesis of disulfide-linked side-chain-to-tail cyclic peptides featuring an N-terminal modification handle(2018)
Authors: Dorien Van Lysebetten, Stefania Felissati, Eirini Antonatou, Lieselot Carrette, Pieter Espeel, Evelien Focquet, Filip Du Prez, Annemieke Madder
Pages: 641 - 646 - Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities(2017)
Authors: Anish Parmar, Stephen H Prior, Abhishek Iyer, Charlotte S Vincent, Dorien Van Lysebetten, Eefjan Breukink, Annemieke Madder, Edward J Taylor, Ishwar Singh
Pages: 2016 - 2019 - Efficient total syntheses and biological activities of two teixobactin analogues(2016)
Authors: Anish Parmar, Abhishek Iyer, Charlotte S Vincent, Dorien Van Lysebetten, Stephen H Prior, Annemieke Madder, Edward J Taylor, Ishwar Singh
Pages: 6060 - 6063 - Cyclisation of peptides via a thiolactone strategy(2016)Volume: 22
Authors: Dorien Van Lysebetten, Stefania Felissati, Evelien Focquet, Y Abdhouni, Pieter Espeel, Lieselot Carrette, Filip Du Prez, Annemieke Madder
Pages: S210 - S210 - Sequence-selective DNA recognition and enhanced cellular up-take by peptideU+2013steroid conjugates(2015)
Authors: Yara Ruiz Garcia, Abhishek Iyer, Dorien Van Lysebetten, Y Vladimir Pabon, Benoit Louage, Malgorzata Honcharenko, Bruno De Geest, CI Edvard Smith, Roger Strömberg, Annemieke Madder
Pages: 17552 - 17555 - Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake(2015)
Authors: Abhishek Iyer, Dorien Van Lysebetten, Yara Ruiz Garcia, Benoit Louage, Bruno De Geest, Annemieke Madder
Pages: 3856 - 3862