Researcher
Björn Menten
- Keywords:prenatal genetic testing, genomics, whole genome sequencing, long read sequencing, preimplantation genetic testing
- Disciplines:Epigenetics, Analysis of next-generation sequence data, Bioinformatics of disease, Bioinformatics data integration and network biology, Data visualisation and high-throughput image analysis, Ontologies, data curation and text mining, Development of bioinformatics software, tools and databases, Immunogenetics, Clinical genetics and molecular diagnostics, Medical epigenomics, Medical metagenomics, Medical genomics, Single-cell data analysis, Genetics, Structural bioinformatics and computational proteomics, Bioinformatics and computational biology not elsewhere classified
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Dean's Office of the Faculty of Medicine and Health Sciences (Administrative office)
Member
From1 Oct 2003 → 30 Sep 2005 - Department of Pediatrics and medical genetics (Department)
Member
From1 Feb 2003 → 30 Sep 2018
Projects
1 - 10 of 25
- Safety first: optimizing artificial oocyte creation through diploid cell haploidizationFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Nuclear Transfer for female-related infertility and mitochondrial diseasesFrom1 Oct 2023 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Application of the Nuclear Transfer technology to overcome female-related infertilityFrom1 Oct 2023 → TodayFunding: BOF - mobility
- Long-read sequencing for the detection of cryptic structural variation in patients with intellectual disability and congenital anomaliesFrom16 Sep 2023 → TodayFunding: BOF - doctoral mandates
- Detection of somatic mutations and disease-defining methylation patterns in brain tissue and cerebrospinal fluid of patients with non-acquired focal epilepsyFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Cofunding core facility - UGent NGS CoreFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine developmentFrom1 Jan 2021 → TodayFunding: BOF - projects
- Non-invasive prenatal screening for the presymptomatic detection of pregnancy complicationsFrom1 Jul 2020 → 30 Jun 2022Funding: IOF - technology validation in lab
- Precision medicine in inherited blindness using integrated omics in human and animal modelsFrom1 Jan 2020 → TodayFunding: BOF - projects
- In-depth comparison and feasibility assessment of an integrated pipeline for neoantigen identification and HLA ligandome sequencing in a clinical settingFrom1 Nov 2019 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 47
- Implicit bias in diagnosing mosaicism amongst preimplantation genetic testing providers : results from a multicenter study of 36 395 blastocysts(2024)
Authors: Mina Popovic, Lorena Borot, Aline R. Lorenzon, Ana Luiza Rossi de Castro Lopes, Denny Sakkas, Belen Lledo, Ruth Morales, Jose Antonio Ortiz, Nikolaos Polyzos, Monica Parriego, et al.
Pages: 258 - 274 - Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage(2023)
Authors: Lore Billiet, Laurenz De Cock, Guillem Sanchez Sanchez, Rupert Mayer, Glenn Goetgeluk, Stijn De Munter, Melissa Pille, Joline Ingels, Hanne Jansen, Karin Weening, et al.
- Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos(2023)
Authors: Bieke Bekaert, Annekatrien Boel, Lisa De Witte, Winter Vandenberghe, Mina Popovic, Panagiotis Stamatiadis, Gwenny Cosemans, Athina-Maria De Loore, Susana Marina Chuva de Sousa Lopes, Petra De Sutter, et al.
Pages: 2326 - 2341 - Structural variants disrupt a critical regulatory region downstream of FOXG1(2023)Volume: 31
Authors: Eva D'haene, Lies Vantomme, Björn Menten, Bert Callewaert, Elfride De Baere, Sarah Vergult
Pages: 28 - 28 - Spindle transfer rescues poor embryo development of in vitro matured ovarian tissue oocytes from transgender men(2022)Volume: 37
Authors: Antonia Christodoulaki, H. He, M. Zhou, Arantxa Cardona Barberán, Chloë De Roo, S. M. Chuva De Sousa Lopes, Björn Menten, Ann Van Soom, Petra De Sutter, Annekatrien Boel, et al.
Number of pages: 1 - Application of an ultrasensitive NGS-based blood test for the diagnosis of early-stage lung cancer : sensitivity, a hurdle still difficult to overcome(2022)
Authors: Malaïka Van der Linden, Bram Van Gaever, Lennart Raman, Karim Vermaelen, Ingel Demedts, Veerle Surmont, Ulrike Himpe, Yolande Lievens, Liesbeth Ferdinande, Franceska Dedeurwaerdere, et al.
- Transcriptional and functional consequences of alterations to MEF2C and its topological organization in neuronal models(2022)
Authors: Kiana Mohajeri, Rachita Yadav, Eva D'haene, Philip M. Boone, Serkan Erdin, Dadi Gao, Mariana Moyses-Oliveira, Riya Bhavsar, Benjamin B. Currall, Kathryn O'Keefe, et al.
Pages: 2049 - 2067 - A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 (ZFHX3) gene(2022)
Authors: Maria del Rocio Pérez Baca, Eva Jacobs, Lies Vantomme, Pontus LeBlanc, Elke Bogaert, Annelies Dheedene, Laurenz De Cock, Bart Dermaut, Aidin Foroutan, Jennifer Kerkhof, et al.
Number of pages: 1 - Benchmarking of long-read structural variant callers on a recently released truth set using Oxford Nanopore data(2021)
Authors: Griet De Clercq, Bram Van Gaever, Lies Vantomme, Annelies Dheedene, Björn Menten
Number of pages: 1 - Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions(2021)
Authors: Liselot Mus, Stéphane Van Haver, Mina Popovic, Wim Trypsteen, Steve Lefever, Nadja Zeltner, Yudelca Ogando, Eva Jacobs, Geertrui Denecker, Ellen Sanders, et al.
Pages: 272 - 281