Researcher
Sarah Gerlo
- Keywords:cellular stress, signal transduction, inflammation, molecular biology
- Disciplines:Cell signalling, Molecular and cell biology not elsewhere classified, Inflammation, Innate immunity
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Biochemistry (Department)
Member
From1 Feb 2011 → 30 Sep 2018 - Department of Physiology (Department)
Member
From1 Jan 2009 → 31 Jan 2011 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2005 → 31 Dec 2008
Projects
1 - 10 of 10
- Generation of a dynamic spatial map of the cellular landscape of HIV-infected gut and its application in unraveling the role of tissue-resident T cells in HIVFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- HIV Nanoheroes: novel CRISPR/Cas9-based CD4+ cell-specific HHV-7 vectors to cure HIVFrom1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- HIGH-THROUGHPUT, HIGH-SENSITIVITY AND COST-EFFECTIVE MONITORING OF INNATE AND ADAPTIVE IMMUNE RESPONSES AT SINGLE CELL LEVELFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- How do ILCs go wrong: unravelling the mechanisms of ILC depletion and functions in HIV infectionFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Automated system for high-pure extraction of RNA and DNA from samples of limited quantity.From1 Dec 2020 → 30 Nov 2022Funding: BOF - scientific equipment program
- COVID-Trace: from tracking virus-host interactions at the single-cell level to tracing cellular markers for clinical patient stratification.From22 May 2020 → 31 May 2021Funding: FWO Special Call for Covid-19 research projects
- Covid-Track: applying quantitative virology and single-cell genomics to unravel the virus-host interactions leading to severe immunopathologies in COVID-19 patientsFrom15 Apr 2020 → 14 Apr 2021Funding: BOF - projects
- Use of bispecific AcTakines to boost innate and adaptive immune responses after acute HIV-1 infectionFrom15 Nov 2019 → 13 Jan 2024Funding: BOF - doctoral mandates
- Preclinical evaluation of chemogenetics as new treatment for drug-resistant epilepsyFrom1 Jan 2019 → 31 Dec 2022Funding: FWO Strategic Basic Research Grant
- Special Research Fund Professorship in molecular biologyFrom1 Feb 2011 → 31 Jan 2021Funding: BOF - ZAP BOF mandates
Publications
1 - 10 of 16
- Unraveling ongoing inflammation after early ART by in-depth analysis of lymph nodes(2023)
Authors: Jozefien De Clercq, Kathleen Busman-Sahay, Laurens Lambrechts, Sofie Rutsaert, Sol Taylor-Brill, Stephen Bondoc, Marie-Angélique De Scheerder, Jacob Estes, Sarah Gerlo, Linos Vandekerckhove
Number of pages: 1 - Rethinking IL-1 antagonism in respiratory viral infections : a role for IL-1 signaling in the development of antiviral T cell immunity(2023)
Authors: Bram Van Den Eeckhout, Marlies Ballegeer, Jozefien De Clercq, Elianne Burg, Xavier Saelens, Linos Vandekerckhove, Sarah Gerlo
- Humoral and cellular responses to COVID-19 vaccination indicate the need for post-vaccination testing in frail population(2022)
Authors: Wojciech Witkowski, Sarah Gerlo, Magdalena Wejda, Delphine Acar, Steven Callens, Stefan Heytens, Elizaveta Padalko, Hannelore Vercruysse, Piet Cools, Linos Vandekerckhove
- End of dose interval symptoms in patients treated with natalizumab : a role for serum cytokines?(2020)
Authors: Cathérine Dekeyser, Annelien De Pue, Anne Sieben, Luc Algoed, Liesbeth Van Hijfte, Sarah Gerlo, Guy Laureys
- A novel Stat1 mutation leading to hyperphosphorylation in a patient with Pneumocystis jjiroveci and chronic mucocutaneous candidiasis(2014)Volume: 34
Authors: Melissa Dullaers, Jens Staal, Sarah Gerlo, Elien Vandermarliere, V Debacker, Victoria Bordon Maria, K De Waele, I Meyts, L Moens, X Bossuyt, et al.
Pages: S443 - S444 - A combined 'omics' approach identifies NMI as a novel cytokine-induced regulator of IRE1 alpha and JNK in pancreatic beta cells(2014)Volume: 57
Authors: F Brozzi, Sarah Gerlo, FA Grieco, Samuel Lievens, C Gysemans, L Marselli, P Marchetti, C Mathieu, Jan Tavernier, DL Eizirik
Pages: S181 - S181 - MAPPIT and Co: the importance of system artifacts(2013)Volume: 63
Authors: Jan Tavernier, Leentje De Ceuninck, Sarah Gerlo, Irma Lemmens, Samuel Lievens, José Van Der Heyden, Joris Wauman
Pages: 303 - 304 - Dual effects of β2-adrenergic receptor on NF-κB-dependent genes: synergy versus inhibition(2011)Volume: 59
Authors: G Laureys, Anneleen Spooren, R Clinckers, J De Keyser, Guy Haegeman, Sarah Gerlo
Pages: S142 - S142 - IL-1 beta stabilizes IL-6 mRNA in human astrocytoma cells(2010)Volume: 228
Authors: Anneleen Spooren, Guy Haegeman, Sarah Gerlo
Pages: 22 - 23 - Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols(2010)
Authors: Samlee Mankhetkorn, Wilart Poompimon, Ajay Palagani, Sergey Zhokhov, Sarah Gerlo, Guy Haegeman, Wim Vanden Berghe
Patents
1 - 9 of 9
- CD8 BINDING AGENTS (Inventor)
- Hybrid CAR and Hybrid TCR cells to treat infectious diseases (Inventor)
- CLEC9A BINDING AGENTS AND USE THEREOF (Inventor)
- FUSOKINES INVOLVING CYTOKINES WITH STRONGLY REDUCED RECEPTOR BINDING AFFINITIES (Inventor)
- TARGETED MODIFIED IL-1 FAMILY MEMBERS (Inventor)
- TARGETED MODIFIED IL-1 FAMILY MEMBERS (Inventor)
- FUSOKINES INVOLVING CYTOKINES WITH STRONGLY REDUCED RECEPTOR BINDING AFFINITIES (Inventor)
- CLEC9A BINDING AGENTS AND USE THEREOF (Inventor)
- CD8 BINDING AGENTS (Inventor)