Researcher
Lotte Vermeulen
- Disciplines:Medicinal products, Pharmacognosy and phytochemistry, Pharmaceutics, Biomarker discovery and evaluation, Other pharmaceutical sciences, Drug discovery and development, Toxicology and toxinology, Pharmacotherapy, Pharmacology
Affiliations
- Department of Pharmaceutics (Department)
Member
From16 Sep 2013 → 23 Sep 2018
Projects
1 - 1 of 1
- Non-viral gene therapy: overcoming the endosomal barrierFrom1 Jan 2014 → 31 Dec 2017Funding: IWT personal funding - specialisation scholarships
Publications
1 - 8 of 8
- Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis(2020)
Authors: Juan Fraire, Gaƫlle Houthaeve, Jing Liu, Laurens Raes, Lotte Vermeulen, Stephan Stremersch, Toon Brans, Gerardo Garcia-Diaz Barriga, Sarah De Keulenaer, Filip Van Nieuwerburgh, et al.
Pages: 262 - 275 - The proton sponge hypothesis : fable or fact?(2018)
Authors: Lotte Vermeulen, Katrien Remaut, Kevin Braeckmans
Pages: 184 - 190 - Quantifying the average number of nucleic acid therapeutics per nanocarrier by single particle tracking microscopy(2018)
Authors: Elisa Zagato, Lotte Vermeulen, Heleen Dewitte, Griet Van Imschoot, Kristiaan Neyts, Katrien Remaut, Kevin Braeckmans
Pages: 1142 - 1149 - Investigating the intracellular delivery of non-viral gene therapeutics : a focus on the endosomal barrier(2018)
Authors: Lotte Vermeulen
- Methodologies to investigate intracellular barriers for nucleic acid delivery in non-viral gene therapy(2018)
Authors: Lotte Vermeulen, Toon Brans, Katrien Remaut, Kevin Braeckmans
Pages: 74 - 90 - Endosomal size and membrane leakiness influence proton sponge-based rupture of endosomal vesicles(2018)
Authors: Lotte Vermeulen, Toon Brans, Sangram Keshari Samal, Katrien Remaut, Kevin Braeckmans
Pages: 2332 - 2345 - Photothermally triggered endosomal escape and its influence on transfection efficiency of gold-functionalized JetPEI/pDNA nanoparticles(2018)
Authors: Lotte Vermeulen, Juan Fraire, Laurens Raes, Ellen De Meester, Sarah De Keulenaer, Filip Van Nieuwerburgh, Katrien Remaut, Kevin Braeckmans
- Design of smart GE11-PLGA/PEG-PLGA blend nanoparticulate platforms for parenteral administration of hydrophilic macromolecular drugs : synthesis, preparation and in vitro/ex vivo characterization(2016)
Authors: Barbara Colzani, Giovanna Speranza, Rossella Dorati, Bice Conti, Tiziana Modena, Giovanna Bruni, Elisa Zagato, Lotte Vermeulen, George Dakwar, Kevin Braeckmans, et al.
Pages: 1112 - 1123