Researcher
Tom Delanghe
- Disciplines:Biophysics, Molecular and cell biology, Laboratory medicine, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From8 Sep 2016 → Today
Projects
1 - 1 of 1
- Unraveling the role of RIPK1 phosphorylation in TNF-mediated cell
death and inflammationFrom1 Jan 2017 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 10
- NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis(2023)
Authors: Yves Dondelinger, Dario Priem, Jon Huyghe, Tom Delanghe, Peter Vandenabeele, Mathieu Bertrand
- RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD(2023)
Authors: Hannelore Van Eeckhoutte, Chantal Donovan, Richard Y. Kim, Thomas M. Conlon, Meshal Ansari, Haroon Khan, Ranjith Jayaraman, Nicole G. Hansbro, Yves Dondelinger, Tom Delanghe, et al.
- The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach(2022)
Authors: Pauline Puylaert, Isabelle Coornaert, Cedric H. G. Neutel, Yves Dondelinger, Tom Delanghe, Mathieu Bertrand, Pieter-Jan Guns, Guido R. Y. De Meyer, Wim Martinet
- Unraveling the role of RIPK1 phosphorylation in TNF-mediated cell death and inflammation(2021)
Authors: Tom Delanghe
- Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor(2021)
Authors: Tom Delanghe, Jon Huyghe, Seungheon Lee, Dario Priem, Samya Van Coillie, Barbara Gilbert, Peter Vandenabeele, Alexei Degterev, Gregory D. Cuny, Yves Dondelinger, et al.
- RIPK1 kinase-dependent death : a symphony of phosphorylation events(2020)
Authors: Tom Delanghe, Yves Dondelinger, Mathieu Bertrand
Pages: 189 - 200 - Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation(2020)
Authors: Lucie Laurien, Masahiro Nagata, Hannah Schünke, Tom Delanghe, Janica L. Wiederstein, Snehlata Kumari, Robin Schwarzer, Teresa Corona, Marcus Krüger, Mathieu Bertrand, et al.
- Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation(2019)
Authors: Yves Dondelinger, Tom Delanghe, Dario Priem, Meghan A Wynosky-Dolfi, Daniel Sorobetea, Diego Rojas Rivera, Piero Giansanti, Ria Roelandt, Julia Gropengiesser, Klaus Ruckdeschel, et al.
- MK2 puts an additional brake on RIPK1 cytotoxic potential(2018)
Authors: Yves Dondelinger, Tom Delanghe, Mathieu Bertrand
Pages: 457 - 459 - MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death(2017)
Authors: Yves Dondelinger, Tom Delanghe, Diego Rojas Rivera, Dario Priem, Tinneke Delvaeye, Inge Bruggeman, Franky Van Herreweghe, Peter Vandenabeele, Mathieu Bertrand
Pages: 1237 - 1247