Researcher
Lennart Zabeau
- Disciplines:Palliative care and end-of-life care, Laboratory medicine, Other translational sciences, Regenerative medicine, Nursing, Other clinical sciences, Other basic sciences, Other paramedical sciences, Other health sciences, Other medical and health sciences
Affiliations
- Department of Biochemistry (Department)
Member
From1 Oct 1998 → 31 Mar 2017
Projects
1 - 1 of 1
- Detailed analysis of mechanisms of leptin receptor activation and the development of leptin receptor antagonists.From1 Oct 2007 → 30 Sep 2010Funding: FWO fellowships, BOF - Other initiatives
Publications
1 - 10 of 19
- Leptin receptor antagonism of iNKT cell function : a novel strategy to combat multiple myeloma(2017)
Authors: E Menu, K Vanderkerken, S Faict, K Maes, E De Bruyne, Michael Drennan, X Leleu, Lennart Zabeau, Jan Tavernier
Pages: 2678 - 2685 - The leptin receptor complex : heavier than expected?(2017)
Authors: Joris Wauman, Lennart Zabeau, Jan Tavernier
Pages: 1 - 20 - Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level(2015)
Authors: Lennart Zabeau, Cathy J Jensen, Sylvie Seeuws, Geert van Loo, Hui Chen, Ken Walder, Jacob Hollis, Simon Foote, Margaret J Morris, José Van Der Heyden, et al.
Pages: 629 - 644 - 20 Years of leptin: insights into signaling assemblies of the leptin receptor(2014)
Authors: Lennart Zabeau, Kedar Moharana, Savvas Savvides, Jan Tavernier
Pages: T9 - T23 - Structural and mechanistic paradigm of leptin receptor activation revealed by complexes with wild-type and antagonist leptins(2014)
Authors: Kedar Moharana, Lennart Zabeau, Philippe Ringler, Henning Stahlberg, Jan Tavernier, Savvas Savvides
Pages: 866 - 877 - A bidirectional crosstalk between iNKT cells and adipocytes mediated by leptin modulates susceptibility for T cell mediated hepatitis(2014)
Authors: Sylvie Seeuws, Lennart Zabeau, Tine Decruy, Julie Coudenys, Fien Windels, Michael Drennan, Akihiko Yoshimura, Jan Tavernier
Pages: 175 - 182 - Selection of non-competitive leptin antagonists using a random nanobody-based approach(2012)
Authors: Lennart Zabeau, Liesbeth Faes, Sylvie Seeuws, Tine Decruy, Jan Tavernier
Pages: 425 - 434 - Kinetics of leptin binding to the Q223R leptin receptor
Authors: Hans Verkerke, Caitlin Naylor, Lennart Zabeau, Jan Tavernier, William A, Jr Petri, Chelsea Marie
- Leptin attenuates lipopolysaccharide-induced apoptosis of thymocytes partially via down-regulation of cPLA2 and p38 MAPK activation
Authors: Chen Liang, Jie Liao, Zihui Deng, Cuihong Song, Jinying Zhang, Lennart Zabeau, Jan Tavernier, Kai Zhang, Hui Xue, Guangtao Yan
Pages: 620 - 627 - An abnormally glycosylated isoform of erythropoietin in hemangioblastoma is associated with polycythemia
Authors: Sigurd E Delanghe, Jan Dierick, Thomas Maenhout, Lennart Zabeau, Jan Tavernier, Joris Bleyen
Pages: 304 - 306
Patents
1 - 6 of 6
- TARGETED MUTANT INTERFERON-GAMMA AND USES THEREOF (Inventor)
- MODULATION OF DENDRITIC CELL LINEAGES (Inventor)
- TARGETED MUTANT INTERFERON-GAMMA AND USES THEREOF (Inventor)
- MODULATION OF DENDRITIC CELL LINEAGES (Inventor)
- TARGETING OF CYTOKINE ANTAGONISTS (Inventor)
- TARGETED MUTANT INTERFERON-GAMMA AND USES THEREOF (Inventor)