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Organisation
Department of Dermatology
Department
Lifecycle:1 Jan 1993 → 30 Sep 2018
Organisation profile:The Clinic for Skin Diseases aims to provide high quality and contemporary qualitative dermatological care to patients within a framework that integrates scientific research, academic training and social needs in an innovative way.
Keywords:Dermatologie
Disciplines:Dermatology
Projects
1 - 10 of 11
- Translational study of prostaglandin E2-induced indoleamine 2,3- dioxygenase in vitiligo: from bench to bedsideFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- The role of exosomal non-coding RNAs in melanoma metastasisFrom1 Oct 2017 → 30 Sep 2021Funding: FWO fellowships
- Randomized phase II clinical trial on TriMixDC-MEL adjuvant autologous dendritic cell therapy in combination with PD-1 blockade following the resection of melanoma macro-metastasesFrom1 Oct 2016 → 30 Sep 2019Funding: Nonprofit institution or equivalents
- Translational study of the inflammatory aspects of vitiligo: unraveling the danger modelFrom1 Oct 2014 → 30 Sep 2017Funding: BOF - Other initiatives
- evaluation of the cost benefit of a skin cancer screening methodFrom1 May 2013 → 31 Dec 2020Funding: Foreign foundations, funds with scientific view
- Further exploration of the role of indoleamine 2,3-dioxygenase (IDO) as a possible mechanism of immune-escape in melanoma.From1 Oct 2012 → 31 Aug 2015Funding: FWO fellowships, BOF - Other initiatives
- Investigation of the predictive value of baseline gene expression and NDA methylation profiling for the activity of CTLA-4 blockade and dendritic cell therapy in patients with advanced melanomaFrom1 Sep 2012 → 31 Aug 2016Funding: Nonprofit institution or equivalents
- Detailed studie of the role of type-I IFN in TNF-induced and TNF-mediated pathologiesFrom1 Oct 2010 → 5 Jan 2016Funding: IWT personal funding - specialisation scholarships
- Study of determinants in the immune escape of melanoma and identification of possible strategies to reverse this escape.From1 Oct 2010 → 30 Sep 2012Funding: BOF - Doctoral projects
- Synthesis and characterization of non-viral liposomal carriers for the local application of siRNA molecules and antagomirs therapeutic treatment of psoriasisFrom1 Oct 2009 → 26 Feb 2015Funding: IWT personal funding - specialisation scholarships
Publications
1 - 10 of 16
- Design, development and characterization of lipid-based nanosomes for siRNA delivery into human skin
Authors: Barbara Geusens
- RNA interference of myosin Va exon F isoforms in primary human melanocytes: an alternative to treat hyperpigmentation(2008)Volume: 128
Authors: Mireille Van Gele, Barbara Geusens, I LAMBERT
Pages: 220 - Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin(2010)
Authors: Barbara Geusens, Mireille Van Gele, Sien Braat, Marc CA Stuart, Tarl W Prow, Washington Sanchez, Michael S Roberts, Niek Sanders
Pages: 4077 - 4090 - miR-145 overexpression suppresses the migration and invasion of metastatic melanoma cells(2013)
Authors: Peter Dynoodt, Reinhart Speeckaert, Ines Chevolet, Lieve Brochez, Mireille Van Gele
Pages: 1443 - 1451 - Revealing the role of miR-145 as a key player in melanogenesis and melanoma
Authors: Peter Dynoodt
- Knockdown of myosin Va isoforms by RNAi as a tool to block melanosome transport in primary human melanocytes(2008)
Authors: Mireille Van Gele, Barbara Geusens, AM SCHMITT, L AGUILAR, Jo Lambert
Pages: 2474 - 2484 - Development of a 3D pigmented skin model to evaluate RNAi-induced depigmentation(2011)
Authors: Mireille Van Gele, Barbara Geusens, Reinhart Speeckaert, Peter Dynoodt, Barbara Vanhoecke, Karolien Van Den Bossche
Pages: 773 - 775 - Lipid-mediated gene delivery to the skin(2011)
Authors: Barbara Geusens, TINE STROBBE, Stefanie Bracke, Peter Dynoodt, Niek Sanders, Mireille Van Gele
Pages: 199 - 211 - Ultradeformable liposomes for delivery of small interfering RNA (siRNA) into human primary melanocytes(2008)Volume: 128
Authors: Barbara Geusens, Mireille Van Gele, S DE SMEDT, N SANDERS, I LAMBERT
Pages: 220 - Cutaneous short-interfering RNA therapy(2009)
Authors: Barbara Geusens, Niek Sanders, Tarl Prow, Mireille Van Gele
Pages: 1333 - 1349