Researcher
Tom De Bruyn
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Drug Delivery and Disposition (Division)
Member
From1 Feb 2009 → 31 Jan 2014
Projects
1 - 1 of 1
- Development and evaluation of new strategies for pharmacokinetical boosting.From1 Feb 2009 → 10 Jan 2014Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 11
- Confocal imaging with a fluorescent bile acid analogue closely mimicking hepatic taurocholate disposition(2014)
Authors: Tom De Bruyn, Wouter Sempels, Nico Holmstock, Sagnik Chatterjee, Patrick Augustijns, Johan Hofkens, Hideaki Mizuno, Pieter Annaert
Pages: 1872 - 1881 - Transporter-based boosting of HIV protease inhibitors(2014)
Authors: Tom De Bruyn, Pieter Annaert, Patrick Augustijns
- Structure–based identification of OATP1B1/3 inhibitors(2013)
Authors: Tom De Bruyn, Peter de Witte, Patrick Augustijns, Pieter Annaert
Pages: 1257 - 1267 - Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine(2013)
Authors: Nico Holmstock, Tom De Bruyn, Jan Bevernage, Pieter Annaert, Jan Tack, Patrick Augustijns
Pages: 27 - 32 - Sandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity(2013)
Authors: Tom De Bruyn, Sagnik Chatterjee, Sarinj Fattah, Janneke Keemink, Johan Nicolaï, Patrick Augustijns, Pieter Annaert
Pages: 589 - 616 - Stability of therapeutic albumin solutions used for molecular adsorbent recirculating system-based liver dialysis(2012)
Authors: Tom De Bruyn, Björn Meijers, Pieter Evenepoel, Ludo Willems, Patrick Augustijns, Pieter Annaert
Pages: 29 - 41 - Sodium fluorescein is a probe substrate for hepatic drug transport mediated by OATP1B1 and OATP1B3(2011)
Authors: Tom De Bruyn, Sarinj Fattah, Patrick Augustijns, Pieter Annaert
Pages: 5018 - 5030 - Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes(2011)
Authors: Tom De Bruyn, Myriam Baes, Patrick Augustijns, Pieter Annaert
Pages: 297 - 307 - Characterization of NTCP, OATP and OCT function in human cryopreserved hepatocytes in suspension(2010)
Authors: Tom De Bruyn, Zhi-Wei Ye Ye, Jasminder Sahi, Patrick Augustijns, Pieter Annaert
Pages: 164 - 164 - Charactrization of the In Vitro Uptake Mechanism and Kinetics of Sodium Fluorescein in Suspended Rat Hepatocytes(2010)
Authors: Sarinj Fattah, Tom De Bruyn, Patrick Augustijns, Pieter Annaert
Pages: 290 - 290