Researcher
Lien Spans
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Laboratory for Cytogenetics and Genome Research (Division)
Member
From1 Jan 2017 → 31 Dec 2017 - Laboratory for Genetics of Malignant Disorders (Division)
Member
From1 Jan 2015 → 31 Dec 2016 - Laboratory of Molecular Endocrinology (Division)
Member
From1 Sep 2009 → 31 Dec 2014
Publications
1 - 10 of 31
- Establishment and Characterization of Advanced Penile Cancer Patient-derived Tumor Xenografts: Paving the Way for Personalized Treatments(2022)
Authors: Anne-Sophie Van Rompuy, Eduard Roussel, Lien Spans, Maria Francesca Baietti, Eleonora Leucci, Maarten Albersen
Pages: 1787 - 1794 - Generation of patient-derived models from a metastatic pediatric diffuse leptomeningeal glioneuronal tumor with KIAA1549::BRAF fusion(2022)
Authors: Julie Messiaen, Lien Spans, Anne Uyttebroeck, Bart Depreitere, Isabelle Vanden Bempt, Raf Sciot, Frederik De Smet
Pages: 793 - 797 - Targeted RNA sequencing for upfront analysis of actionable driver alterations in non-small cell lung cancer(2022)
Authors: Sofie Claerhout, Lien Spans, Christophe Dooms, Els Wauters, Johan Vansteenkiste, Birgit Weynand
Pages: 242 - 249 - Detection of MDM2 amplification by shallow whole genome sequencing of cell-free DNA of patients with dedifferentiated liposarcoma(2022)
Authors: Lien Spans, Maria Debiec-Rychter
- Comprehensive immunomolecular profiling of endometrial carcinoma: A tertiary retrospective study(2021)
Authors: Sara Vander Borght, Lien Spans, Hilde Brems, Annouschka Laenen, Ignace Vergote, Toon Van Gorp, Els Van Nieuwenhuysen, Sileny Han, Stefan Timmerman, Anne-Sophie Van Rompuy, et al.
Pages: 694 - 701 - Comprehensive targeted next-generation sequencing approach in the molecular diagnosis of gastrointestinal stromal tumor(2021)
Authors: Isabelle Vanden Bempt, Sara Vander Borght, Raf Sciot, Lien Spans, Hilde Brems, Baki Topal, Patrick Schöffski, Eric Legius, Maria Debiec-Rychter
Pages: 239 - 249 - Establishment, Characterization, and Imaging of a First Platinum-resistant Penile Cancer Patient-derived Xenograft in Nude Mice: A eUROGEN Project(2020)
Authors: Uwe Himmelreich, Christopher Cawthorne, Christophe Deroose, Willy Gsell, Lien Spans, Eleonora Leucci, Anne-Sophie Van Rompuy, Maarten Albersen
Pages: 294 - 296 - Detection of Circulating Tumor DNA in Patients With Uterine Leiomyomas(2019)
Authors: Lien Spans, Maria Debiec-Rychter
- Describing the Reportable Range Is Important for Reliable Treatment Decisions A Multiple Laboratory Study for Molecular Tumor Profiling Using Next-Generation Sequencing(2018)
Authors: Véronique Tack, Lien Spans, Cleo Keppens, Els Dequeker
Pages: 743 - 753 - Combination approach for detecting different types of alterations in circulating tumor DNA in leiomyosarcoma(2018)
Authors: Lien Spans, Maria Debiec-Rychter
Pages: 2688 - 2699