Researcher
H Llewelyn Roderick
- Disciplines:Physiology, Cell growth and development, Cell signalling, Epigenetics, Intracellular compartments and transport
Affiliations
- Experimental Cardiology (Division)
Responsible
From1 Oct 2023 → Today - Experimental Cardiology (Division)
Member
From1 Oct 2014 → Today
Projects
1 - 10 of 22
- Deciphering Molecular Pathways of Hypoxia Sensitivity in Adult Cardiomyocytes: An Integrative Cross-Species InvestigationFrom1 Apr 2024 → TodayFunding: Other federal public and semi-governmental institutions
- Connexin-43 Hemichannels as pro-arythmic mediators in Cardiac Hypertrophy and Heart FailureFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Understanding how neutrophil extracellular traps (NETs) contribute to vulnerability of the ageing heartFrom1 Oct 2022 → TodayFunding: FWO fellowships
- Investigating the role of DNA methylation in the failing and in the ageing heartFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Subcellular Ca2+ signalling microdomains regulating cardiomyocyte growth and functionsFrom19 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Spatially-Organized 3D Human Cardiac Bilayer Models for Duchenne Cardiomyopathy Modelling and Drug DiscoveryFrom23 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Cell-cell interactions and the role of tissue microarchitecture in cardiac arrhythmias after myocardial infarctionFrom15 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigating the Role and Opportunities of DNA methylation in the Ageing Heart.From1 Oct 2021 → 30 Sep 2022Funding: BOF - postdoctoral mandates
- Understanding the vulnerability of the ageing heartFrom1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Subcellular Ca2+ signalling microdomains regulating cardiomyocyte growth and functionFrom30 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 80
- Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development.(2023)
Authors: H Llewelyn Roderick
Pages: 100135 - The ryanodine receptor microdomain in cardiomyocytes(2023)
Authors: Eef Dries, Guillaume Gilbert, H Llewelyn Roderick, Karin Sipido
- Heterogeneity of Repolarization and Cell-Cell Variability of Cardiomyocyte Remodeling Within the Myocardial Infarction Border Zone Contribute to Arrhythmia Susceptibility.(2023)
Authors: Dylan Vermoortele, Guillaume Gilbert, Mohamad Youness, Bernard Thienpont, Rik Willems, H Llewelyn Roderick, Piet Claus, Karin Sipido
- InsP3R-RyR channel crosstalk augments sarcoplasmic reticulum Ca2+ release and arrhythmogenic activity in post-MI pig cardiomyocytes.(2023)
Authors: Joshua Jeen Tung Chung, Eef Dries, Piet Claus, Karin Sipido, H Llewelyn Roderick
Pages: 47 - 59 - Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments(2023)
Authors: H Llewelyn Roderick, Geert Bultynck, Karin Sipido
- DEG (differentially expressed gene) or not DEG that is the question: Should we compare between datasets or not?(2023)
Authors: H Llewelyn Roderick
- Reversal of Right Ventricular Remodeling After Correction of Pulmonary Regurgitation in Tetralogy of Fallot(2023)
Authors: Bjorn Cools, Katrien Vandendriessche, Joeri Van Puyvelde, Mohamad Youness, H Llewelyn Roderick, Marc Gewillig, Karin Sipido, Piet Claus, Filip Rega
Pages: 301 - 305 - IP3R activity increases propensity of RyR-mediated sparks by elevating dyadic [Ca2+].(2023)
Authors: Joshua Jeen Tung Chung, H Llewelyn Roderick
- Cardiomyocyte differentiation from human induced pluripotent stem cells is delayed following knockout of Bcl-2(2023)
Authors: Tim Vervliet, Robin Duelen, Rita La Rovere, H Llewelyn Roderick, Maurilio Sampaolesi
- InsP3R-RyR Ca2+ channel crosstalk facilitates arrhythmias in the failing human ventricle(2022)
Authors: Guillaume Gilbert, Eef Dries, Rosa Donate Puertas, Ashutosh Tomar, Tobie Martens, Pieter Vanden Berghe, Filip Rega, Karin Sipido, H Llewelyn Roderick